Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics

Convenient access to comprehensive data on therapeutic targets is crucial for drug discovery. This paper details a significant update to the Therapeutic Target Database (TTD). The 2018 version includes new information on: drug resistance mutations, differential expression profiles of targets in patient tissues, expression profiles in healthy tissues, and target combinations. This enrichment makes TTD a more powerful resource for facilitating patient-focused research, discovery, and clinical investigation of targeted therapeutics.

Recommended citation: Li, Y. H., Yu, C. Y., Li, X. X., Zhang, P., Tang, J., Yang, Q., Fu, T., Zhang, X., Cui, X., Tu, G., Zhang, Y., Li, S., Yang, F., Sun, Q., Qin, C., Zeng, X., Chen, Z., Chen, Y. Z., & Zhu, F. (2018). "Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics." Nucleic Acids Research. 46(D1):D1121-D1127.
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